Revertants of a transcription termination mutant of yeast contain diverse genetic alterations

J Kotval, KS Zaret, S Consaul, F Sherman - Genetics, 1983 - academic.oup.com
Revertants of the cyc1-512 transcription termination mutant of the yeast Saccharomyces
cerevisiae were isolated and subjected to a detailed genetic analysis. The cyc1-512
mutation previously was shown to be a 38-base pair deletion that causes only 10% of the
normal steady-state levels of CYC1 mRNA and of the CYC1 gene product, iso-1-cytochrome
c. Forty-one cyc1-512 revertants were classified by their content of iso-1-cytochrome c and
by their genetic properties in meiotic crosses. Many of the revertants contain local genetic …
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